TYPE A BEHAVIOR: AN EPIDEMIOLOGIC STUDY OF TWIN FAMILIE

  • Meininger, Janet C, (PI)

Project: Research project

Description

Familial aggregation of the Type A behavior pattern, its components and
standard risk factors for coronary heart disease (total cholesterol and
trigylcerides, HDL-C and LDL-C, systolic and diastolic blood pressure and
relative weight) will be investigated. The sample for this epidemiologic
study will consist of 275 twin pairs, six to eleven years old, and their
parents. Genetic and environmental sources of variation will be
ascertained by comparing monozygotic pairs with same-sex dizygotic pairs.
Opposite-sex twins will be analyzed as matched pairs to examine sex
differences in the Type A behavior pattern among children. It will be
determine whether or not the Type A behavior pattern or its components is
correlated with any of the standard risk factors in this pediatric
population. Familial aggregation of these characteristics will be studied
using data on the twins and their parents. It is important to identify the extent to which the Type A behavior pattern
in children can be attributed to genetic factors. Once this has been
accomplished it will be necessary to determine the specific environmental
factors that interact with the propensity to develop this risk factor. It
is anticipated that the results of this study will provide insight into the
origins of the Type A behavior pattern.
StatusFinished
Effective start/end date7/1/846/30/87

Funding

  • National Institutes of Health

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Epidemiologic Studies
Blood Pressure
Child Behavior
HDL Cholesterol
Coronary Disease
Parents
Weights and Measures

Keywords

  • Medicine(all)