Psychological distress in cancer patients in a large Chinese cross-sectional study

Wen Wang Rao, Ming Jia Yang, Bo Nan Cao, Yue Yue You, Yang Yu Zhang, Ying Yu Liu, Changgui Kou, Yaqin Yu, Ryan M. Cassidy, Qiong Yu, Xiang Y Zhang

Research output: Contribution to journalArticle

Abstract

Background: Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with chronic disease patients without cancer, or 2) healthy controls in a large representative sample of Chinese population. Methods: Using a multistage, stratified cluster sampling method, 21,101 subjects 18–79 years old were interviewed face-to-face in Jilin province, China. Their psychological status was assessed with the 12-item General Health Questionnaire (GHQ-12). A total score of ≥4 was used as the threshold for determining psychological distress. Results: The prevalence of psychological distress was 14.08% across the entire sample: 10.63% in healthy controls; 14.81% in patients with chronic diseases; and 20% in patients with cancer. Multiple logistic regression analysis indicated that, as compared to the health controls, both cancer (OR = 1.609, 95%CI = 1.245–2.081) and chronic disease patients (OR = 1.330, 95%CI = 1.189–1.478) were more likely to suffer from psychological distress. Moreover, cancer patients had a higher risk of psychological distress than patients with chronic diseases (OR = 1.295, 95%CI = 1.049–1.600; p = 0.016). In addition, the cancer group (2.68 ± 0.114) demonstrated a higher GHQ score than the patients with chronic diseases (2.30 ± 0.017) and healthy controls (1.98 ± 0.029) (both p < 0.001). Conclusion: Our results showed both a higher rate and greater degree of psychological distress in patients with cancer. This suggests a need for better psychological management in cancer patients to help alleviate their distress.

LanguageEnglish
Pages950-956
Number of pages7
JournalJournal of Affective Disorders
Volume245
DOIs
StatePublished - Feb 15 2019

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Cross-Sectional Studies
Psychology
Neoplasms
Chronic Disease
Health
China
Logistic Models
Odds Ratio
Regression Analysis

Keywords

  • Association
  • Cancers
  • China
  • Chronic diseases
  • Psychological distress

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Rao, W. W., Yang, M. J., Cao, B. N., You, Y. Y., Zhang, Y. Y., Liu, Y. Y., ... Zhang, X. Y. (2019). Psychological distress in cancer patients in a large Chinese cross-sectional study. Journal of Affective Disorders, 245, 950-956. https://doi.org/10.1016/j.jad.2018.11.089

Psychological distress in cancer patients in a large Chinese cross-sectional study. / Rao, Wen Wang; Yang, Ming Jia; Cao, Bo Nan; You, Yue Yue; Zhang, Yang Yu; Liu, Ying Yu; Kou, Changgui; Yu, Yaqin; Cassidy, Ryan M.; Yu, Qiong; Zhang, Xiang Y.

In: Journal of Affective Disorders, Vol. 245, 15.02.2019, p. 950-956.

Research output: Contribution to journalArticle

Rao, WW, Yang, MJ, Cao, BN, You, YY, Zhang, YY, Liu, YY, Kou, C, Yu, Y, Cassidy, RM, Yu, Q & Zhang, XY 2019, 'Psychological distress in cancer patients in a large Chinese cross-sectional study', Journal of Affective Disorders, vol. 245, pp. 950-956. https://doi.org/10.1016/j.jad.2018.11.089
Rao, Wen Wang ; Yang, Ming Jia ; Cao, Bo Nan ; You, Yue Yue ; Zhang, Yang Yu ; Liu, Ying Yu ; Kou, Changgui ; Yu, Yaqin ; Cassidy, Ryan M. ; Yu, Qiong ; Zhang, Xiang Y. / Psychological distress in cancer patients in a large Chinese cross-sectional study. In: Journal of Affective Disorders. 2019 ; Vol. 245. pp. 950-956.
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abstract = "Background: Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with chronic disease patients without cancer, or 2) healthy controls in a large representative sample of Chinese population. Methods: Using a multistage, stratified cluster sampling method, 21,101 subjects 18–79 years old were interviewed face-to-face in Jilin province, China. Their psychological status was assessed with the 12-item General Health Questionnaire (GHQ-12). A total score of ≥4 was used as the threshold for determining psychological distress. Results: The prevalence of psychological distress was 14.08{\%} across the entire sample: 10.63{\%} in healthy controls; 14.81{\%} in patients with chronic diseases; and 20{\%} in patients with cancer. Multiple logistic regression analysis indicated that, as compared to the health controls, both cancer (OR = 1.609, 95{\%}CI = 1.245–2.081) and chronic disease patients (OR = 1.330, 95{\%}CI = 1.189–1.478) were more likely to suffer from psychological distress. Moreover, cancer patients had a higher risk of psychological distress than patients with chronic diseases (OR = 1.295, 95{\%}CI = 1.049–1.600; p = 0.016). In addition, the cancer group (2.68 ± 0.114) demonstrated a higher GHQ score than the patients with chronic diseases (2.30 ± 0.017) and healthy controls (1.98 ± 0.029) (both p < 0.001). Conclusion: Our results showed both a higher rate and greater degree of psychological distress in patients with cancer. This suggests a need for better psychological management in cancer patients to help alleviate their distress.",
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AU - Rao, Wen Wang

AU - Yang, Ming Jia

AU - Cao, Bo Nan

AU - You, Yue Yue

AU - Zhang, Yang Yu

AU - Liu, Ying Yu

AU - Kou, Changgui

AU - Yu, Yaqin

AU - Cassidy, Ryan M.

AU - Yu, Qiong

AU - Zhang, Xiang Y

PY - 2019/2/15

Y1 - 2019/2/15

N2 - Background: Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with chronic disease patients without cancer, or 2) healthy controls in a large representative sample of Chinese population. Methods: Using a multistage, stratified cluster sampling method, 21,101 subjects 18–79 years old were interviewed face-to-face in Jilin province, China. Their psychological status was assessed with the 12-item General Health Questionnaire (GHQ-12). A total score of ≥4 was used as the threshold for determining psychological distress. Results: The prevalence of psychological distress was 14.08% across the entire sample: 10.63% in healthy controls; 14.81% in patients with chronic diseases; and 20% in patients with cancer. Multiple logistic regression analysis indicated that, as compared to the health controls, both cancer (OR = 1.609, 95%CI = 1.245–2.081) and chronic disease patients (OR = 1.330, 95%CI = 1.189–1.478) were more likely to suffer from psychological distress. Moreover, cancer patients had a higher risk of psychological distress than patients with chronic diseases (OR = 1.295, 95%CI = 1.049–1.600; p = 0.016). In addition, the cancer group (2.68 ± 0.114) demonstrated a higher GHQ score than the patients with chronic diseases (2.30 ± 0.017) and healthy controls (1.98 ± 0.029) (both p < 0.001). Conclusion: Our results showed both a higher rate and greater degree of psychological distress in patients with cancer. This suggests a need for better psychological management in cancer patients to help alleviate their distress.

AB - Background: Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with chronic disease patients without cancer, or 2) healthy controls in a large representative sample of Chinese population. Methods: Using a multistage, stratified cluster sampling method, 21,101 subjects 18–79 years old were interviewed face-to-face in Jilin province, China. Their psychological status was assessed with the 12-item General Health Questionnaire (GHQ-12). A total score of ≥4 was used as the threshold for determining psychological distress. Results: The prevalence of psychological distress was 14.08% across the entire sample: 10.63% in healthy controls; 14.81% in patients with chronic diseases; and 20% in patients with cancer. Multiple logistic regression analysis indicated that, as compared to the health controls, both cancer (OR = 1.609, 95%CI = 1.245–2.081) and chronic disease patients (OR = 1.330, 95%CI = 1.189–1.478) were more likely to suffer from psychological distress. Moreover, cancer patients had a higher risk of psychological distress than patients with chronic diseases (OR = 1.295, 95%CI = 1.049–1.600; p = 0.016). In addition, the cancer group (2.68 ± 0.114) demonstrated a higher GHQ score than the patients with chronic diseases (2.30 ± 0.017) and healthy controls (1.98 ± 0.029) (both p < 0.001). Conclusion: Our results showed both a higher rate and greater degree of psychological distress in patients with cancer. This suggests a need for better psychological management in cancer patients to help alleviate their distress.

KW - Association

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KW - China

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